A large-scale research collaboration designed to advance the field of human genetics and precision medicine has been announced.

The program – to be undertaken by Regeneron and the Colorado Center for Personalized Medicine (CCPM) – will share 450,000 DNA samples and corresponding health records from de-identified, consented patient participants in the expansive UCHealth system. The Regeneron Genetics Center (RGC), will sequence these samples, producing genomic data that can be used to facilitate translational medical research and ultimately enable physicians to make better decisions for their patients. 

The CCPM is one of the largest health data warehouses in the US and a pioneer in the use of a secure cloud platform with more than 8.7 million de-identified patient records. The five-year old research enterprise is also one of the first and largest programs in the country to integrate personalized genomic information with clinical data via a research biobank. CCPM physicians will validate any genetic findings from the RGC data in their CLIA-certified lab, enabling the return of clinically-actionable results to patients.

“This collaboration will take an already notable program at the CCPM and expand the depth and breadth of its capabilities, allowing us to give more back to our patient participants than ever before,” said Kathleen Barnes, Ph.D., Professor and director of CCPM at the University of Colorado Anschutz Medical Campus. “We have made tremendous strides with our work in pharmacogenomics, but having access to such a large genomic dataset that enables the return of clinically actionable results will be transformative.